tech and geek stuff
Age reversal drug may be on sale in three years
In early experiments, the drug nicotinamide mononucleotide (NMN) had a dramatic rejuvenating effect on ageing mice.Researchers hope to begin testing the drug on clinical trial patients in the next six...
In lucrative deal, infamous pharma company bails on drug it priced at $89K
EnlargeGetty | PeopleImages reader comments 11 Share this story The pharmaceutical company that drew swift criticism last month for pricing an old, cheap drug at $89,000 per patient, per year has now...
Drug company CEO has trouble with patients paying his prices
Too many diabetics in the U.S. are inadvertently getting stuck with a big bill, making it imperative that drugmakers and middlemen at the heart of the country’s complex pricing system fix the issue before...
Lawsuit: Greedy drug maker purposefully flooded black market with opioids
EnlargeGetty | Pureradiancephoto reader comments 16 Share this story After spending millions to combat the opioid epidemic ravaging its citizens, the working-class city of Everett, Washington, is taking...
Drugmakers fall as investors see pricing threat from Trump
Just before the stock market opened on Tuesday, President Trump said he is working on “a new system” to reduce prices. Prescription drug distributor Express Scripts and biotech company Gilead Sciences...
Pharma CEO insists $89,000 drug will be affordable for patients
CHICAGO — When Marathon Pharmaceuticals’ $89,000 price for a year’s supply of its newly approved muscular dystrophy drug sparked outrage this month, the company’s CEO responded with another figure: $20....
What do we know about the effects of medical marijuana?
EnlargeCalifornia Medical Cannabis Initiative reader comments 9 Share this story BOSTON—Stacy Gruber of Harvard Medical School laid out the numbers: 28 states and the District of Columbia have medical...
Marathon gets the Shkreli treatment from industry after $89K drug dust up
ccPixs.com reader comments 6 Share this story Last week, Marathon Pharmaceuticals announced that it would start selling an old steroid drug that treats Duchenne muscular dystrophy for a whopping $89,000...
Drug maker pushes pause on $89K drug after outcry
Enlarge / Sen. Bernie Sanders (I-VT) Getty | Chip Somodevilla / reader comments 29 Share this story In an unexpected move, Marathon Pharmaceuticals announced Monday that it is pausing the roll-out of...
Old, generic drug for rare disease gets new price tag: $89,000 per year
EnlargeGetty | Boston Globe reader comments 0 Share this story Remember when that pharmaceutical trade group launched a flashy ad campaign to convince consumers that they were different from the price-gouging...
Pharma companies consider discounts if drugs don’t work
Pharmaceutical giants have an answer that doesn’t involve lowering list prices: refunding some of the money to insurers if a drug doesn’t work as expected. [...] the number of such agreements between...
Drug compound halts Alzheimer's-related damage in mice
In some people, the normal brain protein tau collects into toxic tangles that damage brain cells and contributes to diseases such as Alzheimer's. Now, researchers report that they have found a drug can...
Disgraced Shkreli launches website to shame pharma greed, sleaze
Martin Shkreli, former CEO of Turing, smirked his way through Thursday's Congressional hearing.CSPAN reader comments 3 Share this story This week, a pharmaceutical trade group stepped up its efforts to...
New FDA chief should have medical experience, drugmakers say
President-elect Donald Trump’s pick to lead the Food and Drug Administration should have a medical background, and the agency should continue evaluating new medications’ effectiveness, drugmaker executives...
Texas slams FDA with lawsuit for holding up imported execution drugs
Enlarge / A Texas death chamber in Huntsville, Texas.Getty | Joe Raedle reader comments 0 Share this story Texas officials filed a federal lawsuit against the Food and Drug Administration Tuesday following...
New muscle disease treatment comes at a hefty price
The Food and Drug Administration has approved the first drug to treat patients with spinal muscular atrophy, a disease that, in its most severe form, kills infants before they turn 2. Geoffrey Porges,...
Nvidia leads S&P’s winners for 2016, drug stocks slump
Goldman Sachs helped a rally in financial companies and Caterpillar contributed to an industrial boom on Wall Street, while drug companies like Mylan suffered big drops. Nvidia’s stock jumped after each...
Once a teenage science project, pharma startup trades on Nasdaq
Andrew Ritter, the 34-year-old founder of Ritter Pharmaceuticals in Los Angeles, created the original form of the firm’s lead experimental drug by testing it on himself when he was in eighth grade. In...
FDA clears ovarian cancer drug for hard-to-treat tumors
WASHINGTON — Federal health officials have approved a new option for some women battling ovarian cancer: a drug that attacks a genetic mutation seen in a subset of hard-to-treat tumors. The Food and Drug...
Feds begin crackdown on generic drug price fixing, nail two former execs
EnlargeGetty | Roberto Machado Noa reader comments 1 Share this story The Justice Department charged former executives of a pharmaceutical firm with fixing generic drug prices, rigging bids, and conspiring...
Vapers experimenting with illegal drugs bought on the dark web
On the riseDan Kitwood/GettyBy Ian JonesMILLIONS of people worldwide use e-cigarettes or vaping equipment instead of smoking tobacco. But nicotine isn’t the only drug people are vaping. Some vapers are...
In landslide vote, Senate boosts Biden’s moonshot, weakens FDA drug testing
Enlarge / Vice President Joe Biden stops to speak with reporters in the Senate Reception Room following the cloture vote on the "21st Century Cures Act" in the Capitol on Monday, December 5, 2016. Getty...
More at-risk people will get access to HIV preventive treatment
PrEP on trialMike Kear/Alamy Stock PhotoMORE people in England are set to get a preventive HIV treatment, but it still won’t be available to all who want it. PrEP involves taking a drug that reduces the...
The dangers of thinking Australian high school kids just schooled Shkreli
Enlarge / Martin Shkreli, decidedly unaffected.Getty | Eduardo Munoz Alvarez reader comments 30 Share this story A group of high school students in Sydney, Australia are having their moment of fame after...
FDA’s OK on trial opens possibility of prescription ecstasy in five years
Enlarge / Girl with an ecstasy tablet on her tongue, smiley faced pill, UK 2004 (Photo by Universal Images Group via Getty Images)Getty | UniversalImagesGroup reader comments 11 Share this story The Food...
Teens outsmart ‘most hated man’
Martin Shkreli has been outsmarted by a group of teens. REMEMBER Martin Shkreli, the “Big Pharma Bro” described as the most hated man in the world? The pharmaceutical executive worth an estimated $100...
Why the ‘war on drugs’ needs to change
Greens leader Richard Di Natale says there needs to be a major change in how we address illegal drugs. Picture: Andy Brownbill GREENS leader Richard Di Natale says the “war of drugs” has failed and has...
How MDMA changed my life
Psychedelic drugs have been known to cure addiction, depression and anxiety. INSIDE the backyard of a south Sydney property, a postmodern shaman grows a selection of psychedelic plants he says he uses...
Ultra-long acting pill offers new hope in eliminating malaria
Imagine swallowing a pill today that continues releasing the daily dose of a medicine you need for the next week, month or even longer. Investigators have developed a long-acting drug delivery capsule...
Pfizer profit plunges, cholesterol drug dropped
Drugmaker Pfizer topped off a difficult third quarter with news that it’s scrapping a closely watched experimental cholesterol drug, partly due to expectations that insurers would limit access so much...
Aussie cops make $5m drug bust
More than 2000 cannabis plants, MDMA and other drugs with an estimated potential street value of $5 million have been seized in the Northern Rivers. Picture: NSW Police MORE than 2000 cannabis plants,...
DEA reverses decision on kratom; drug stays legal for now
EnlargeGetty | Joe Raedle reader comments 20 Share this story The Drug Enforcement Administration is withdrawing its plan to ban the opioid-like herbal drug kratom—at least for now—according to a preliminary...
Better drug made by identifying the proteins of our ancestors
Enlarge / The structure of the human factor VIII.University of Washington reader comments 0 Share this story Rational drug design seems so promising. So, you know, rational. How could it not work? Here’s...
Thalidomide: Understanding the purity and chirality of drugs and their metabolites
It was the Softenon disaster that made the pharmaceutical industry fully aware of the importance of knowing the enantiomeric purity and chirality of drugs and their metabolites. This disaster involved...
Children with fatal muscle disease walk after drug breakthrough
Next on the list:Huntington’sZEPHYR/SCIENCE PHOTO LIBRARYBy Michael Le Page“TO SEE children who would have been dead sitting and standing is something I never thought I would see.” Francesco Muntoni,...
Patient groups, with loyalties split, sidestep drug price debate
Public anger over the cost of drugs has burned hot for a year, coursing through social media, popping up on the presidential campaign, and erupting in a series of congressional hearings, including one...
DEA has kratom users holding their breath, lawmakers write more letters
EnlargeGetty | Joe Raedle reader comments 33 Share this story Starting today, the Drug Enforcement Administration is free to list a popular herbal supplement called kratom as a Schedule I controlled substance....
Feds go after Mylan for scamming Medicaid out of millions on EpiPen pricing
Enlarge / WASHINGTON, DC - SEPTEMBER 21: Mylan Inc. CEO Heather Bresch holds up a 2-pack of EpiPen as she testifies during a hearing before the House Oversight and Government Reform Committee September...
Senators ask Justice Department to investigate EpiPen maker
WASHINGTON — Senators are asking the Justice Department to investigate whether pharmaceutical company Mylan acted illegally when it classified its lifesaving EpiPen as a generic drug and qualified for...
Scientists turn superbugs into sitting ducks with evolutionary hoodwink
Eric Erbe, Christopher Pooley, USDA reader comments 0 Share this story Bacteria are wizzes at developing resistance to our most powerful antibiotics. This unfortunate skill leads to millions of difficult-to-treat...
Could sex hormones help addicted women stop taking opioids?
John Moore/GettyBy Mallory Locklear Men and women show different patterns of drug abuse, with women becoming addicted to some substances much more quickly. Now a study in rats has found that sex hormones...
New drug clears malaria from mice in a single dose
Enlarge / The drug is what chemists might refer to as a bit of a beast.John Timmer reader comments 10 Share this story Last year, there were over 200 million cases of malaria, and they resulted in nearly...
Express Scripts wants tighter coverage of anti-inflammatory drugs
Americans have expressed outrage at drug companies for raising prices on products like EpiPen, the severe allergy treatment needed by thousands of children, and Daraprim, a rarely used but essential drug...
Alabama cop cradles baby she saved after both parents overdose on drugs
It’s a simple yet striking image: An Alabama police officer is seen holding a little girl in her arms.But it’s the context surrounding the photo that has caused it to go viral. On Tuesday police in Birmingham,...
Researchers cautiously optimistic about new brain-clearing Alzheimer’s drug
EnlargeGetty | Brian B. Bettencourt reader comments 19 Share this story A new Alzheimer’s disease drug may be able to clear away goopy piles of toxic proteins in patients' brains—hallmarks of the progressive...
Putting healthcare first can save festival drug users from harm
Bad trip? This wayBoom Festival/Joao CuritiBy Kevin FranciottiDRUGS at music festivals have made headlines again of late. There have been deaths, and some people have ended up with mental health problems....
Mind-controlled nanobots could release drugs inside your brain
Nanorobots have released drugs inside cockroaches, prompted by only a human thoughtJoel Sartore, National Geographic Photo Ark/GettyBy Helen ThomsonA man has used thought alone to control nanorobots inside...
Darknet drug dealers rake in millions each month
reader comments 8 Share this story The successors to Silk Road, the darknet drug market shut down by the FBI in 2013, are raking in tens of millions of pounds in total revenue every month, according to...
Triple-whammy drug kills parasites that make 20 million sick
Taking out several parasites at once may be key to treating diseasesJackie Lewin, EM Unit, Royal Free Hospital/SPLBy Emily BensonThere’s a new hope for treating three parasitic diseases that together...
Virtual development of real drugs
Inside the human body, the same drug can interact with multiple molecules. This phenomenon is known as 'polypharmacology' and, according to the interaction, a drug can cure a disease or cause side effects...
Business News Roundup, July 13
The Dow Jones industrial average joined the S&P 500 index to close at a fresh record, with U.S. equities climbing a third day as crude rallied and Alcoa Inc.’s results bolstered optimism on corporate...
Spiraling drug costs prompt call for major Medicare changes
WASHINGTON — Calling the rising cost of drugs “unsustainable,” congressional advisers on Wednesday recommended major changes to Medicare’s popular outpatient prescription program, now 10 years old. The...
New drug clears psoriasis in clinical trials
About 80 percent of patients with moderate to severe psoriasis saw their disease completely or almost completely cleared with a new drug called ixekizumab, according to three large, long-term clinical...
Second-in-command at Silk Road 2.0 sentenced to 8 years in prison
Further ReadingTop Silk Road 2.0 admin “DoctorClu” pleads guilty, could face 8 years in prisonBrian Farell told feds: "You're not going to find much of a bigger fish than me."The second-highest administrator...
Will Australia emulate US heroin crisis?
Upper Darby Police in Delaware County, Pennsylvania, released surveillance footage on February 23 showing a man injecting himself with heroin on a public bus and passing out on February 18. Police reportedly...
Vermont on the cusp of enacting the country’s first anti-Shkreli law
CSPANIn a matter of weeks, Vermont could be the first state to require drug makers to justify steep price increases for medications. The bill that would set that requirement has already passed through...
Medical mystery: How tainted drugs “froze” young people—but kickstarted Parkinson’s research
In 1982, a tainted drug caused a handful of young Californians to become mysteriously frozen, unable to move. Their doctor’s ensuing investigation helped catalyze the start of modern Parkinson’s disease...
Database helps researchers connect exposures to health effects, compare diseases
Two new studies give researchers new strategies for connecting environmental exposures to human health effects. To determine whether a drug can be used to treat more than one disease, scientists look for...
Mutual fund industry exhorts drugmakers to defend pricing
In a sign of how U.S. political pressure to rein in drug pricing is weighing on pharmaceutical companies and their investors, a group of major funds called an unusual meeting with top biotech and pharmaceutical...
State chemist was high daily, thousands of drug prosecutions jeopardized
ibblA former Massachusetts drug-lab chemist was high on the job nearly every day for eight years, according to a report from the state's attorney general. The report said that the chemist, Sonja Farak,...
Google under fire for ads running with offensive content
Google makes tens of billions of dollars per year in ad sales. This week it's facing a global crisis after some of the world's biggest advertisers halted their spending after concerns that their ads are...
Google is streamlining its chat apps again
Google has a baffling array of chat apps and platforms out there at the moment, so the tech behemoth has decided to try and simplify its approach just a little bit: firstly it's phasing out Google Talk...
Google reportedly removing SMS texting from Hangouts on May 22
Welcome to your new Hangout. reader comments 40 Share this story Google continues to shake up its messaging tools with the upcoming removal of a popular feature from Hangouts. According to an email sent...
Alphabet Chairman Eric Schmidt: We 'can't guarantee' ads won't appear next to offensive content
Google may not be able to guarantee advertisements won't appear next to offensive content, but it is working on a solution that "can get pretty close," according to Alphabet's executive chairman Eric...
I regard the brain as a computer which will stop working when its component fail. There is no heaven or afterlife for broken-down computers. That is a fairy story for people afraid of the dark