tech and geek stuff
Shares of drugmaker that targets gene mutations soar after positive study results
Shares of Sarepta Therapeutics soared about 15 percent in premarket trading on Wednesday after the company reported positive results from a clinical trial of an experimental medicine for Duchenne muscular...
Australia plans random drug tests for people receiving welfare
Not much help?imageBROKER / Alamy Stock PhotoBy Alice KleinThe Australian government is planning a two-year trial of random drug tests for welfare recipients starting in January 2018. If approved by parliament,...
What drug-addled zebrafish can tell us about addiction
New methods for treating the rising opioid epidemic in America may be found in the brains and behavior of drug-addicted tropical fish, says a new study. A team of researchers from the University of Utah...
How Silicon Valley rediscovered LSD
San Francisco became the acid capital of the world in the 1960s, when hippies, inspired to alter their consciousness by Buddhists and Native Americans, ran wild. Now, the city is spearheading the microdosing...
Side effects kill thousands but our data on them is flawed
Kill or cure? Some drugs have unwanted side effectsSkhoward/GettyBy Mallory LocklearSide effects are a serious problem. As many as 40,000 people in the US die from drug side effects a year. To tackle...
Biotech FibroGen soars more than 50% on positive lung disease treatment study
Shares of FibroGen are soaring more than 50 percent in pre-market trading Tuesday after the biotech reported positive study results for a potential blockbuster drug. The biotech company's drug pamrevlumab,...
Finally, the first new drug for sickle cell anemia in 20 years
In early July the Food and Drug Administration approved the first new drug for sickle cell patients in nearly 20 years. It was a watershed moment for people who suffer from the rare blood disorder that...
We may finally be able to slow Parkinson’s, with a diabetes drug
Parkinson’s takes away the control of movement Kristina Kohanova/EyeEm/GettyBy Jessica HamzelouA diabetes drug can slow the progress of Parkinson’s disease, and seems to target the underlying cause of...
Cramer: Mea culpa! This stock's action is why I say small-cap biotechs are only for speculation
After the stock of Alder BioPharmaceuticals fell off a cliff, plummeting to just over $12 on Thursday from its $55 peak two years ago, Jim Cramer had to find out what went wrong. The decline was only...
Anxiety drug may prevent common virus that causes birth defects
There is no vaccine for cytomegalovirusJames Cavallini/SPLBy Linda GeddesAn anxiety drug could prevent a common virus from causing birth defects and deafness, a study in newborn mice suggests. Roughly...
Police warned of drug so powerful it can kill in one breath
Drew Angerer/Getty ImagesBy Mallory LocklearThe US opioid epidemic may be getting even worse. Preliminary data suggests overdoses are soaring, while law enforcement officials have been warned about the...
Drug that boosts confidence in your own actions may help OCD
Maybe going back to check the door is locked is a good idea after allWestend61/GettyBy Helen ThomsonLife is full of decisions, and sometimes it’s difficult to know if you’re making the right one. But...
Could cannabis help crack cocaine addicts kick the habit?
Time to case the joint?Teryoshi/plainpictureBy Andy CoghlanCOMPONENTS of cannabis might help those addicted to crack cocaine to quit. Such people may find it easier to curb their usage or give up entirely...
Is ADHD a sleep disorder? Stimulant drug improves symptoms
Being alert is hard with ADHDRobert Ormerod/Millennium Images, UKBy Alice KleinA DRUG normally used to treat narcolepsy and excessive daytime sleepiness also seems to improve symptoms of attention deficit...
Drug side effects emerge after approval, study finds
Almost one-third of new drugs approved by federal regulators over a decade ended up years later with warnings about unexpected, sometimes life-threatening side effects or complications, a new analysis...
Cheap stroke drug boosts pancreatic cancer survival in mice
A stroke drug could also bust through the shield surrounding pancreatic tumoursDr. Stanley Flegler/Visuals Unlimited, Inc./SCIENCE PHOTO LIBRARYBy Alice KleinA drug that is already used to treat strokes...
Fight against patent for hepatitis C drug that can cost €55,000
Hepatitis C: a deadly diseaseCavallini James/BSIP/Science Photo LibraryA GROUP of charities, led by Médecins Sans Frontières, is fighting to have a drug’s patent revoked by the European Patent Office....
Diabetes drug could be the first to reverse the disease
Type 2 diabetes can require injections of insulinDavid Hay Jones/Science Photo LibraryBy Andy CoghlanNo insulin injections, no avoiding sugar. A daily pill can reverses diabetes symptoms in mice, opening...
Age reversal drug may be on sale in three years
In early experiments, the drug nicotinamide mononucleotide (NMN) had a dramatic rejuvenating effect on ageing mice.Researchers hope to begin testing the drug on clinical trial patients in the next six...
In lucrative deal, infamous pharma company bails on drug it priced at $89K
EnlargeGetty | PeopleImages reader comments 11 Share this story The pharmaceutical company that drew swift criticism last month for pricing an old, cheap drug at $89,000 per patient, per year has now...
Drug company CEO has trouble with patients paying his prices
Too many diabetics in the U.S. are inadvertently getting stuck with a big bill, making it imperative that drugmakers and middlemen at the heart of the country’s complex pricing system fix the issue before...
Lawsuit: Greedy drug maker purposefully flooded black market with opioids
EnlargeGetty | Pureradiancephoto reader comments 16 Share this story After spending millions to combat the opioid epidemic ravaging its citizens, the working-class city of Everett, Washington, is taking...
Drugmakers fall as investors see pricing threat from Trump
Just before the stock market opened on Tuesday, President Trump said he is working on “a new system” to reduce prices. Prescription drug distributor Express Scripts and biotech company Gilead Sciences...
Pharma CEO insists $89,000 drug will be affordable for patients
CHICAGO — When Marathon Pharmaceuticals’ $89,000 price for a year’s supply of its newly approved muscular dystrophy drug sparked outrage this month, the company’s CEO responded with another figure: $20....
What do we know about the effects of medical marijuana?
EnlargeCalifornia Medical Cannabis Initiative reader comments 9 Share this story BOSTON—Stacy Gruber of Harvard Medical School laid out the numbers: 28 states and the District of Columbia have medical...
Marathon gets the Shkreli treatment from industry after $89K drug dust up
ccPixs.com reader comments 6 Share this story Last week, Marathon Pharmaceuticals announced that it would start selling an old steroid drug that treats Duchenne muscular dystrophy for a whopping $89,000...
Drug maker pushes pause on $89K drug after outcry
Enlarge / Sen. Bernie Sanders (I-VT) Getty | Chip Somodevilla / reader comments 29 Share this story In an unexpected move, Marathon Pharmaceuticals announced Monday that it is pausing the roll-out of...
Old, generic drug for rare disease gets new price tag: $89,000 per year
EnlargeGetty | Boston Globe reader comments 0 Share this story Remember when that pharmaceutical trade group launched a flashy ad campaign to convince consumers that they were different from the price-gouging...
Pharma companies consider discounts if drugs don’t work
Pharmaceutical giants have an answer that doesn’t involve lowering list prices: refunding some of the money to insurers if a drug doesn’t work as expected. [...] the number of such agreements between...
Drug compound halts Alzheimer's-related damage in mice
In some people, the normal brain protein tau collects into toxic tangles that damage brain cells and contributes to diseases such as Alzheimer's. Now, researchers report that they have found a drug can...
Disgraced Shkreli launches website to shame pharma greed, sleaze
Martin Shkreli, former CEO of Turing, smirked his way through Thursday's Congressional hearing.CSPAN reader comments 3 Share this story This week, a pharmaceutical trade group stepped up its efforts to...
New FDA chief should have medical experience, drugmakers say
President-elect Donald Trump’s pick to lead the Food and Drug Administration should have a medical background, and the agency should continue evaluating new medications’ effectiveness, drugmaker executives...
Texas slams FDA with lawsuit for holding up imported execution drugs
Enlarge / A Texas death chamber in Huntsville, Texas.Getty | Joe Raedle reader comments 0 Share this story Texas officials filed a federal lawsuit against the Food and Drug Administration Tuesday following...
New muscle disease treatment comes at a hefty price
The Food and Drug Administration has approved the first drug to treat patients with spinal muscular atrophy, a disease that, in its most severe form, kills infants before they turn 2. Geoffrey Porges,...
Nvidia leads S&P’s winners for 2016, drug stocks slump
Goldman Sachs helped a rally in financial companies and Caterpillar contributed to an industrial boom on Wall Street, while drug companies like Mylan suffered big drops. Nvidia’s stock jumped after each...
Once a teenage science project, pharma startup trades on Nasdaq
Andrew Ritter, the 34-year-old founder of Ritter Pharmaceuticals in Los Angeles, created the original form of the firm’s lead experimental drug by testing it on himself when he was in eighth grade. In...
FDA clears ovarian cancer drug for hard-to-treat tumors
WASHINGTON — Federal health officials have approved a new option for some women battling ovarian cancer: a drug that attacks a genetic mutation seen in a subset of hard-to-treat tumors. The Food and Drug...
Feds begin crackdown on generic drug price fixing, nail two former execs
EnlargeGetty | Roberto Machado Noa reader comments 1 Share this story The Justice Department charged former executives of a pharmaceutical firm with fixing generic drug prices, rigging bids, and conspiring...
Vapers experimenting with illegal drugs bought on the dark web
On the riseDan Kitwood/GettyBy Ian JonesMILLIONS of people worldwide use e-cigarettes or vaping equipment instead of smoking tobacco. But nicotine isn’t the only drug people are vaping. Some vapers are...
In landslide vote, Senate boosts Biden’s moonshot, weakens FDA drug testing
Enlarge / Vice President Joe Biden stops to speak with reporters in the Senate Reception Room following the cloture vote on the "21st Century Cures Act" in the Capitol on Monday, December 5, 2016. Getty...
More at-risk people will get access to HIV preventive treatment
PrEP on trialMike Kear/Alamy Stock PhotoMORE people in England are set to get a preventive HIV treatment, but it still won’t be available to all who want it. PrEP involves taking a drug that reduces the...
The dangers of thinking Australian high school kids just schooled Shkreli
Enlarge / Martin Shkreli, decidedly unaffected.Getty | Eduardo Munoz Alvarez reader comments 30 Share this story A group of high school students in Sydney, Australia are having their moment of fame after...
FDA’s OK on trial opens possibility of prescription ecstasy in five years
Enlarge / Girl with an ecstasy tablet on her tongue, smiley faced pill, UK 2004 (Photo by Universal Images Group via Getty Images)Getty | UniversalImagesGroup reader comments 11 Share this story The Food...
Teens outsmart ‘most hated man’
Martin Shkreli has been outsmarted by a group of teens. REMEMBER Martin Shkreli, the “Big Pharma Bro” described as the most hated man in the world? The pharmaceutical executive worth an estimated $100...
Why the ‘war on drugs’ needs to change
Greens leader Richard Di Natale says there needs to be a major change in how we address illegal drugs. Picture: Andy Brownbill GREENS leader Richard Di Natale says the “war of drugs” has failed and has...
How MDMA changed my life
Psychedelic drugs have been known to cure addiction, depression and anxiety. INSIDE the backyard of a south Sydney property, a postmodern shaman grows a selection of psychedelic plants he says he uses...
Ultra-long acting pill offers new hope in eliminating malaria
Imagine swallowing a pill today that continues releasing the daily dose of a medicine you need for the next week, month or even longer. Investigators have developed a long-acting drug delivery capsule...
Pfizer profit plunges, cholesterol drug dropped
Drugmaker Pfizer topped off a difficult third quarter with news that it’s scrapping a closely watched experimental cholesterol drug, partly due to expectations that insurers would limit access so much...
Aussie cops make $5m drug bust
More than 2000 cannabis plants, MDMA and other drugs with an estimated potential street value of $5 million have been seized in the Northern Rivers. Picture: NSW Police MORE than 2000 cannabis plants,...
DEA reverses decision on kratom; drug stays legal for now
EnlargeGetty | Joe Raedle reader comments 20 Share this story The Drug Enforcement Administration is withdrawing its plan to ban the opioid-like herbal drug kratom—at least for now—according to a preliminary...
Better drug made by identifying the proteins of our ancestors
Enlarge / The structure of the human factor VIII.University of Washington reader comments 0 Share this story Rational drug design seems so promising. So, you know, rational. How could it not work? Here’s...
Thalidomide: Understanding the purity and chirality of drugs and their metabolites
It was the Softenon disaster that made the pharmaceutical industry fully aware of the importance of knowing the enantiomeric purity and chirality of drugs and their metabolites. This disaster involved...
Children with fatal muscle disease walk after drug breakthrough
Next on the list:Huntington’sZEPHYR/SCIENCE PHOTO LIBRARYBy Michael Le Page“TO SEE children who would have been dead sitting and standing is something I never thought I would see.” Francesco Muntoni,...
Patient groups, with loyalties split, sidestep drug price debate
Public anger over the cost of drugs has burned hot for a year, coursing through social media, popping up on the presidential campaign, and erupting in a series of congressional hearings, including one...
DEA has kratom users holding their breath, lawmakers write more letters
EnlargeGetty | Joe Raedle reader comments 33 Share this story Starting today, the Drug Enforcement Administration is free to list a popular herbal supplement called kratom as a Schedule I controlled substance....
Feds go after Mylan for scamming Medicaid out of millions on EpiPen pricing
Enlarge / WASHINGTON, DC - SEPTEMBER 21: Mylan Inc. CEO Heather Bresch holds up a 2-pack of EpiPen as she testifies during a hearing before the House Oversight and Government Reform Committee September...
Senators ask Justice Department to investigate EpiPen maker
WASHINGTON — Senators are asking the Justice Department to investigate whether pharmaceutical company Mylan acted illegally when it classified its lifesaving EpiPen as a generic drug and qualified for...
Scientists turn superbugs into sitting ducks with evolutionary hoodwink
Eric Erbe, Christopher Pooley, USDA reader comments 0 Share this story Bacteria are wizzes at developing resistance to our most powerful antibiotics. This unfortunate skill leads to millions of difficult-to-treat...
Could sex hormones help addicted women stop taking opioids?
John Moore/GettyBy Mallory Locklear Men and women show different patterns of drug abuse, with women becoming addicted to some substances much more quickly. Now a study in rats has found that sex hormones...
New drug clears malaria from mice in a single dose
Enlarge / The drug is what chemists might refer to as a bit of a beast.John Timmer reader comments 10 Share this story Last year, there were over 200 million cases of malaria, and they resulted in nearly...
I regard the brain as a computer which will stop working when its component fail. There is no heaven or afterlife for broken-down computers. That is a fairy story for people afraid of the dark